{"id":1233,"date":"2026-03-25T00:15:20","date_gmt":"2026-03-24T15:15:20","guid":{"rendered":"https:\/\/asami.clinic\/male\/?p=1233"},"modified":"2026-04-03T18:00:07","modified_gmt":"2026-04-03T09:00:07","slug":"hormone-hair-loss-cycle-disruption","status":"publish","type":"post","link":"https:\/\/asami.clinic\/male\/men-mechanism\/men-testosterone\/hormone-hair-loss-cycle-disruption\/","title":{"rendered":"\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u8131\u6bdb\u306e\u4ed5\u7d44\u307f\u3068\u306f\uff01\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u304c\u4e71\u308c\u308b\u30d7\u30ed\u30bb\u30b9\u3092\u89e3\u8aac"},"content":{"rendered":"\n<p>\u300c\u6700\u8fd1\u3001\u629c\u3051\u6bdb\u304c\u5897\u3048\u305f\u6c17\u304c\u3059\u308b\u300d\u300c\u751f\u3048\u969b\u304c\u5f8c\u9000\u3057\u3066\u304d\u305f\u304b\u3082\u3057\u308c\u306a\u3044\u300d\u2014\u2014\u305d\u3093\u306a\u4e0d\u5b89\u3092\u611f\u3058\u305f\u3053\u3068\u306e\u3042\u308b\u7537\u6027\u306f\u5c11\u306a\u304f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u306e\u591a\u304f\u306f\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\u3067\u3042\u308bDHT\u304c\u6bdb\u5305\u306b\u4f5c\u7528\u3057\u3001\u9aea\u306e\u6210\u9577\u671f\u3092\u77ed\u7e2e\u3055\u305b\u308b\u3053\u3068\u3067\u9032\u884c\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u8131\u6bdb\u306e\u539f\u56e0\u306f\u30db\u30eb\u30e2\u30f3\u306e\u4ed5\u7d44\u307f\u305d\u306e\u3082\u306e\u306b\u6df1\u304f\u6839\u3056\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30db\u30eb\u30e2\u30f3\u304c\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u3092\u3069\u306e\u3088\u3046\u306b\u4e71\u3057\u3001\u8584\u6bdb\u306b\u3064\u306a\u304c\u308b\u306e\u304b\u3092\u6bb5\u968e\u7684\u306b\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6b63\u3057\u3044\u77e5\u8b58\u3092\u8eab\u306b\u3064\u3051\u308b\u3053\u3068\u3067\u3001\u3054\u81ea\u8eab\u306b\u5408\u3063\u305f\u5bfe\u7b56\u306e\u7b2c\u4e00\u6b69\u3092\u8e0f\u307f\u51fa\u3059\u304d\u3063\u304b\u3051\u306b\u306a\u308c\u3070\u5e78\u3044\u3067\u3059\u3002<\/p>\n\n\n\n\t\t\t\t\t\t\t\t<div id=\"js-sc_mokuji\" class=\"sc_mokuji sc_mokuji-close\">\n\t\t\t\t\t<div class=\"sc_mokuji-title\">\n\t\t\t\t\t\t<span class=\"icon-mokuji\"><\/span>\u76ee\u6b21\uff3b<span class=\"sc_mokuji-toggle\"><\/span>\uff3d\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<ul class=\"sc_mokuji-list pre_close\">\n\t\t\t\t\t<li><a href=\"#toc\"><span class=\"toc_number toc_depth_1 toc_nomal\">1<\/span> \u7537\u6027\u30db\u30eb\u30e2\u30f3\u304c\u9aea\u306e\u6bdb\u306b\u5f71\u97ff\u3059\u308b\u4ed5\u7d44\u307f\u306f\u60f3\u50cf\u4ee5\u4e0a\u306b\u8907\u96d1\u3060\u3063\u305f<\/a><ul><li><a href=\"#toc-2\"><span class=\"toc_number toc_depth_2\">1.1<\/span> \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3060\u3051\u3067\u306f\u8131\u6bdb\u306f\u8d77\u3053\u3089\u306a\u3044<\/a><\/li><li><a href=\"#5DHT\"><span class=\"toc_number toc_depth_2\">1.2<\/span> 5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u304c\u5909\u63db\u3059\u308bDHT\u3068\u3044\u3046\u8131\u6bdb\u56e0\u5b50<\/a><\/li><li><a href=\"#DHT\"><span class=\"toc_number toc_depth_2\">1.3<\/span> DHT\u304c\u6bdb\u4e73\u982d\u7d30\u80de\u306b\u7d50\u5408\u3059\u308b\u3068\u4f55\u304c\u8d77\u304d\u308b\u306e\u304b<\/a><\/li><li><a href=\"#toc-3\"><span class=\"toc_number toc_depth_2\">1.4<\/span> \u907a\u4f1d\u7684\u611f\u53d7\u6027\u304c\u8131\u6bdb\u30ea\u30b9\u30af\u3092\u5de6\u53f3\u3059\u308b<\/a><\/li><\/ul><\/li><li><a href=\"#toc-4\"><span class=\"toc_number toc_depth_1 toc_nomal\">2<\/span> \u5065\u5eb7\u306a\u9aea\u3092\u80b2\u3066\u308b\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u6b63\u5e38\u306a\u6d41\u308c\u3092\u62bc\u3055\u3048\u3088\u3046<\/a><ul><li><a href=\"#toc-5\"><span class=\"toc_number toc_depth_2\">2.1<\/span> \u6210\u9577\u671f\uff08\u30a2\u30ca\u30b2\u30f3\uff09\u306b\u9aea\u306f\u592a\u304f\u9577\u304f\u80b2\u3064<\/a><\/li><li><a href=\"#toc-6\"><span class=\"toc_number toc_depth_2\">2.2<\/span> \u9000\u884c\u671f\uff08\u30ab\u30bf\u30b2\u30f3\uff09\u3067\u6bdb\u6839\u304c\u7e2e\u5c0f\u306b\u5411\u304b\u3046<\/a><\/li><li><a href=\"#toc-7\"><span class=\"toc_number toc_depth_2\">2.3<\/span> \u4f11\u6b62\u671f\uff08\u30c6\u30ed\u30b2\u30f3\uff09\u3092\u7d4c\u3066\u9aea\u306f\u81ea\u7136\u306b\u629c\u3051\u843d\u3061\u308b<\/a><\/li><\/ul><\/li><li><a href=\"#DHT-2\"><span class=\"toc_number toc_depth_1 toc_nomal\">3<\/span> DHT\u304c\u6210\u9577\u671f\u3092\u77ed\u7e2e\u3055\u305b\u3066\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u304c\u4e71\u308c\u308b\u5168\u8c8c<\/a><ul><li><a href=\"#DHTTGF\"><span class=\"toc_number toc_depth_2\">3.1<\/span> DHT\u304c\u6bdb\u4e73\u982d\u304b\u3089TGF-\u03b2\u3092\u5206\u6ccc\u3055\u305b\u6210\u9577\u671f\u3092\u6253\u3061\u5207\u308b<\/a><\/li><li><a href=\"#DKK-1Wnt\"><span class=\"toc_number toc_depth_2\">3.2<\/span> DKK-1\u304cWnt\u30b7\u30b0\u30ca\u30eb\u3092\u906e\u65ad\u3057\u3066\u6bdb\u6bcd\u7d30\u80de\u306e\u5897\u6b96\u3092\u6b62\u3081\u308b<\/a><\/li><li><a href=\"#toc-8\"><span class=\"toc_number toc_depth_2\">3.3<\/span> \u6bdb\u5305\u306e\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u306f\u7e70\u308a\u8fd4\u3057\u306e\u77ed\u7e2e\u30b5\u30a4\u30af\u30eb\u3067\u9032\u884c\u3059\u308b<\/a><\/li><\/ul><\/li><li><a href=\"#toc-9\"><span class=\"toc_number toc_depth_1 toc_nomal\">4<\/span> \u8584\u6bdb\u304c\u9032\u884c\u3059\u308b\u30d1\u30bf\u30fc\u30f3\u306b\u306f\u7537\u6027\u578b\u8131\u6bdb\u75c7\u306a\u3089\u3067\u306f\u306e\u7279\u5fb4\u304c\u3042\u308b<\/a><ul><li><a href=\"#MO\"><span class=\"toc_number toc_depth_2\">4.1<\/span> \u751f\u3048\u969b\u3068\u3064\u3080\u3058\u304b\u3089\u5f8c\u9000\u3059\u308b\u5178\u578b\u7684\u306aM\u5b57\u30fbO\u5b57\u578b<\/a><\/li><li><a href=\"#toc-10\"><span class=\"toc_number toc_depth_2\">4.2<\/span> \u5074\u982d\u90e8\u3068\u5f8c\u982d\u90e8\u304c\u6b8b\u308a\u3084\u3059\u3044\u7406\u7531<\/a><\/li><li><a href=\"#toc-11\"><span class=\"toc_number toc_depth_2\">4.3<\/span> \u9032\u884c\u5ea6\u3092\u6e2c\u308b\u30cf\u30df\u30eb\u30c8\u30f3\u30fb\u30ce\u30fc\u30a6\u30c3\u30c9\u5206\u985e<\/a><\/li><\/ul><\/li><li><a href=\"#toc-12\"><span class=\"toc_number toc_depth_1 toc_nomal\">5<\/span> \u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u4e71\u3059\u751f\u6d3b\u7fd2\u6163\u306b\u5fc3\u5f53\u305f\u308a\u306f\u3042\u308a\u307e\u305b\u3093\u304b\uff1f<\/a><ul><li><a href=\"#toc-13\"><span class=\"toc_number toc_depth_2\">5.1<\/span> \u7761\u7720\u4e0d\u8db3\u304c\u7537\u6027\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/a><\/li><li><a href=\"#toc-14\"><span class=\"toc_number toc_depth_2\">5.2<\/span> \u98df\u751f\u6d3b\u306e\u504f\u308a\u304c\u982d\u76ae\u74b0\u5883\u3092\u60aa\u5316\u3055\u305b\u308b<\/a><\/li><li><a href=\"#toc-15\"><span class=\"toc_number toc_depth_2\">5.3<\/span> \u30b9\u30c8\u30ec\u30b9\u3068\u30db\u30eb\u30e2\u30f3\u306e\u5bc6\u63a5\u306a\u95a2\u4fc2<\/a><\/li><li><a href=\"#DHT-3\"><span class=\"toc_number toc_depth_2\">5.4<\/span> \u904e\u5ea6\u306a\u98f2\u9152\u30fb\u55ab\u7159\u304cDHT\u6fc3\u5ea6\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027<\/a><\/li><\/ul><\/li><li><a href=\"#toc-16\"><span class=\"toc_number toc_depth_1 toc_nomal\">6<\/span> \u533b\u7642\u6a5f\u95a2\u3067\u53d7\u3051\u3089\u308c\u308b\u30db\u30eb\u30e2\u30f3\u6027\u8131\u6bdb\u3078\u306e\u5bfe\u51e6\u6cd5<\/a><ul><li><a href=\"#5\"><span class=\"toc_number toc_depth_2\">6.1<\/span> 5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\uff08\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u30fb\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\uff09<\/a><\/li><li><a href=\"#toc-17\"><span class=\"toc_number toc_depth_2\">6.2<\/span> \u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306e\u8840\u884c\u4fc3\u9032\u4f5c\u7528\u3067\u6bdb\u5305\u3092\u6d3b\u6027\u5316\u3055\u305b\u308b<\/a><\/li><li><a href=\"#toc-18\"><span class=\"toc_number toc_depth_2\">6.3<\/span> \u81ea\u5206\u306b\u5408\u3063\u305f\u80b2\u6bdb\u5264\u9078\u3073\u3067\u62bc\u3055\u3048\u3066\u304a\u304d\u305f\u3044\u6210\u5206<\/a><\/li><\/ul><\/li><li><a href=\"#toc-19\"><span class=\"toc_number toc_depth_1 toc_nomal\">7<\/span> \u65e9\u3081\u306e\u5bfe\u7b56\u304c\u30ab\u30ae\uff5c\u30db\u30eb\u30e2\u30f3\u6027\u8131\u6bdb\u3068\u4e0a\u624b\u306b\u5411\u304d\u5408\u3046\u305f\u3081\u306e\u5fc3\u69cb\u3048<\/a><ul><li><a href=\"#toc-20\"><span class=\"toc_number toc_depth_2\">7.1<\/span> \u8131\u6bdb\u306b\u6c17\u3065\u3044\u305f\u3089\u307e\u305a\u306f\u5c02\u9580\u533b\u306b\u76f8\u8ac7\u3059\u308b\u3079\u304d<\/a><\/li><li><a href=\"#toc-21\"><span class=\"toc_number toc_depth_2\">7.2<\/span> \u7d99\u7d9a\u3057\u305f\u6cbb\u7642\u3068\u30bb\u30eb\u30d5\u30b1\u30a2\u306e\u4e21\u7acb\u304c\u6210\u679c\u306b\u3064\u306a\u304c\u308b<\/a><\/li><li><a href=\"#1\"><span class=\"toc_number toc_depth_2\">7.3<\/span> \u7126\u308a\u306f\u7981\u7269\u3001\u534a\u5e74\u304b\u30891\u5e74\u306e\u30b9\u30d1\u30f3\u3067\u7d4c\u904e\u3092\u898b\u5b88\u308b<\/a><\/li><\/ul><\/li><li><a href=\"#toc-22\"><span class=\"toc_number toc_depth_1 toc_nomal\">8<\/span> \u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li>\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<h2 class=\"wp-block-heading\"><span id=\"toc\">\u7537\u6027\u30db\u30eb\u30e2\u30f3\u304c\u9aea\u306e\u6bdb\u306b\u5f71\u97ff\u3059\u308b\u4ed5\u7d44\u307f\u306f\u60f3\u50cf\u4ee5\u4e0a\u306b\u8907\u96d1\u3060\u3063\u305f<\/span><\/h2>\n\n\n\n<p>\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u306e\u6839\u672c\u539f\u56e0\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u305d\u306e\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u305d\u3053\u304b\u3089\u5909\u63db\u3055\u308c\u308b\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u306b\u3042\u308a\u307e\u3059\u3002DHT\u304c\u6bdb\u4e73\u982d\u7d30\u80de\u306e\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u3068\u7d50\u3073\u3064\u304f\u3053\u3068\u3067\u3001\u6bdb\u5305\u306e\u7e2e\u5c0f\u304c\u5f90\u3005\u306b\u9032\u3093\u3067\u3044\u304f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-2\">\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3060\u3051\u3067\u306f\u8131\u6bdb\u306f\u8d77\u3053\u3089\u306a\u3044<\/span><\/h3>\n\n\n\n<p>\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4ee3\u8868\u683c\u3067\u3042\u308b\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306f\u3001\u7b4b\u8089\u306e\u767a\u9054\u3084\u9aa8\u683c\u306e\u5f62\u6210\u306a\u3069\u3001\u7537\u6027\u306e\u8eab\u4f53\u6a5f\u80fd\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u81ea\u4f53\u304c\u76f4\u63a5\u7684\u306b\u9aea\u306e\u6bdb\u3092\u6e1b\u3089\u3059\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u5b9f\u969b\u306b\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306f\u4f53\u6bdb\u3084\u30d2\u30b2\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u982d\u76ae\u3067\u8131\u6bdb\u3092\u5f15\u304d\u8d77\u3053\u3059\u305f\u3081\u306b\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u304c\u5225\u306e\u7269\u8cea\u306b\u5909\u63db\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"5DHT\">5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u304c\u5909\u63db\u3059\u308bDHT\u3068\u3044\u3046\u8131\u6bdb\u56e0\u5b50<\/span><\/h3>\n\n\n\n<p>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306f\u3001\u982d\u76ae\u306e\u6bdb\u5305\u306b\u5b58\u5728\u3059\u308b\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u300d\u3068\u3044\u3046\u9175\u7d20\u306b\u3088\u3063\u3066DHT\u3078\u3068\u5909\u63db\u3055\u308c\u307e\u3059\u30025\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306b\u306fI\u578b\u3068II\u578b\u304c\u5b58\u5728\u3057\u307e\u3059\u304c\u3001\u8131\u6bdb\u306b\u6df1\u304f\u95a2\u4e0e\u3059\u308b\u306e\u306f\u4e3b\u306bII\u578b\u3067\u3059\u3002<\/p>\n\n\n\n<p>II\u578b\u306e5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306f\u3001\u6bdb\u5305\u306e\u5916\u6bdb\u6839\u9798\uff08\u304c\u3044\u3082\u3046\u3053\u3093\u3057\u3087\u3046\uff1d\u6bdb\u6839\u3092\u5305\u3080\u7d44\u7e54\u306e\u5916\u5074\u90e8\u5206\uff09\u3084\u6bdb\u4e73\u982d\u7d30\u80de\u306b\u591a\u304f\u5206\u5e03\u3057\u3066\u3044\u307e\u3059\u3002\u3068\u304f\u306b\u524d\u982d\u90e8\u3084\u982d\u9802\u90e8\u306e\u6bdb\u5305\u3067\u306f\u3053\u306e\u9175\u7d20\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u8131\u6bdb\u304c\u8d77\u3053\u308a\u3084\u3059\u3044\u90e8\u4f4d\u3068\u4e00\u81f4\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3068DHT\u306e\u9055\u3044<\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>\u9805\u76ee<\/th><th>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3<\/th><th>DHT<\/th><\/tr><\/thead><tbody><tr><td>\u751f\u6210\u5834\u6240<\/td><td>\u4e3b\u306b\u7cbe\u5de3<\/td><td>\u6bdb\u5305\u5185\u3067\u9175\u7d20\u5909\u63db<\/td><\/tr><tr><td>\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u3078\u306e\u7d50\u5408\u529b<\/td><td>\u3084\u3084\u5f31\u3044<\/td><td>\u7d043\u301c5\u500d\u5f37\u3044<\/td><\/tr><tr><td>\u4f53\u6bdb\u3078\u306e\u4f5c\u7528<\/td><td>\u6210\u9577\u3092\u4fc3\u9032<\/td><td>\u982d\u76ae\u3067\u306f\u6291\u5236\u306b\u50cd\u304f<\/td><\/tr><tr><td>\u8840\u4e2d\u6fc3\u5ea6<\/td><td>\u6bd4\u8f03\u7684\u9ad8\u3044<\/td><td>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u7d0410%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"DHT\">DHT\u304c\u6bdb\u4e73\u982d\u7d30\u80de\u306b\u7d50\u5408\u3059\u308b\u3068\u4f55\u304c\u8d77\u304d\u308b\u306e\u304b<\/span><\/h3>\n\n\n\n<p>\u751f\u6210\u3055\u308c\u305fDHT\u306f\u3001\u6bdb\u4e73\u982d\u7d30\u80de\u306b\u5b58\u5728\u3059\u308b\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08AR\uff09\u3068\u7d50\u5408\u3057\u307e\u3059\u3002\u3059\u308b\u3068\u3001DHT-AR\u8907\u5408\u4f53\u304c\u7d30\u80de\u6838\u5185\u3078\u79fb\u884c\u3057\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u30d1\u30bf\u30fc\u30f3\u3092\u5909\u5316\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u7d50\u679c\u3001\u6bdb\u4e73\u982d\u7d30\u80de\u306fTGF-\u03b21\u3084DKK-1\u3068\u3044\u3063\u305f\u6210\u9577\u6291\u5236\u56e0\u5b50\u3092\u5206\u6ccc\u3059\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u56e0\u5b50\u304c\u6bdb\u6bcd\u7d30\u80de\u306e\u5897\u6b96\u3092\u59a8\u3052\u3001\u9aea\u306e\u6210\u9577\u671f\u3092\u77ed\u304f\u3057\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-3\">\u907a\u4f1d\u7684\u611f\u53d7\u6027\u304c\u8131\u6bdb\u30ea\u30b9\u30af\u3092\u5de6\u53f3\u3059\u308b<\/span><\/h3>\n\n\n\n<p>\u540c\u3058\u91cf\u306eDHT\u304c\u5b58\u5728\u3057\u3066\u3082\u3001\u3059\u3079\u3066\u306e\u7537\u6027\u304cAGA\u306b\u306a\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u8131\u6bdb\u304c\u8d77\u3053\u308b\u304b\u3069\u3046\u304b\u306f\u3001\u6bdb\u5305\u306b\u5b58\u5728\u3059\u308b\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u306e\u611f\u53d7\u6027\u306b\u5927\u304d\u304f\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>AR\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u3063\u3066\u53d7\u5bb9\u4f53\u304cDHT\u306b\u5bfe\u3057\u3066\u904e\u654f\u306b\u53cd\u5fdc\u3057\u3084\u3059\u304f\u306a\u308b\u4f53\u8cea\u306e\u65b9\u306f\u3001AGA\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u7684\u7d20\u56e0\u306fX\u67d3\u8272\u4f53\u4e0a\u306b\u4f4d\u7f6e\u3059\u308b\u305f\u3081\u3001\u6bcd\u65b9\u306e\u5bb6\u7cfb\u304b\u3089\u306e\u907a\u4f1d\u304c\u5f71\u97ff\u3059\u308b\u30b1\u30fc\u30b9\u3082\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span id=\"toc-4\">\u5065\u5eb7\u306a\u9aea\u3092\u80b2\u3066\u308b\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u6b63\u5e38\u306a\u6d41\u308c\u3092\u62bc\u3055\u3048\u3088\u3046<\/span><\/h2>\n\n\n\n<p>\u9aea\u306e\u6bdb\u306f\u4e00\u5b9a\u306e\u5468\u671f\u3067\u6210\u9577\u3068\u8131\u843d\u3092\u7e70\u308a\u8fd4\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u5468\u671f\u3092\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\uff08\u6bdb\u5468\u671f\uff09\u3068\u547c\u3073\u307e\u3059\u3002\u6b63\u5e38\u306a\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u3067\u306f\u3001\u6210\u9577\u671f\u304c2\u301c6\u5e74\u3068\u9577\u304f\u7d9a\u304f\u305f\u3081\u3001\u592a\u304f\u3057\u3063\u304b\u308a\u3057\u305f\u9aea\u304c\u7dad\u6301\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-5\">\u6210\u9577\u671f\uff08\u30a2\u30ca\u30b2\u30f3\uff09\u306b\u9aea\u306f\u592a\u304f\u9577\u304f\u80b2\u3064<\/span><\/h3>\n\n\n\n<p>\u6210\u9577\u671f\u306f\u3001\u6bdb\u6bcd\u7d30\u80de\u304c\u6d3b\u767a\u306b\u5206\u88c2\u3057\u3066\u9aea\u3092\u751f\u307f\u51fa\u3059\u671f\u9593\u3067\u3059\u3002\u982d\u9aea\u5168\u4f53\u306e\u7d0485\u301c90%\u304c\u3053\u306e\u6210\u9577\u671f\u306b\u3042\u308a\u3001\u901a\u5e382\u301c6\u5e74\u306b\u308f\u305f\u3063\u3066\u7d9a\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6210\u9577\u671f\u306e\u9577\u3055\u304c\u9aea\u306e\u9577\u3055\u3092\u6c7a\u3081\u308b\u3068\u3044\u3063\u3066\u3082\u904e\u8a00\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u9593\u3001\u6bdb\u4e73\u982d\u304b\u3089\u6804\u990a\u304c\u4f9b\u7d66\u3055\u308c\u3001\u6bdb\u6bcd\u7d30\u80de\u304c\u76db\u3093\u306b\u5897\u6b96\u3059\u308b\u3053\u3068\u3067\u592a\u304f\u4e08\u592b\u306a\u6bdb\u9aea\u304c\u3064\u304f\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-6\">\u9000\u884c\u671f\uff08\u30ab\u30bf\u30b2\u30f3\uff09\u3067\u6bdb\u6839\u304c\u7e2e\u5c0f\u306b\u5411\u304b\u3046<\/span><\/h3>\n\n\n\n<p>\u6210\u9577\u671f\u306e\u7d42\u308f\u308a\u3092\u8fce\u3048\u308b\u3068\u3001\u6bdb\u6bcd\u7d30\u80de\u306e\u5206\u88c2\u304c\u6025\u901f\u306b\u4f4e\u4e0b\u3057\u3001\u9000\u884c\u671f\u3078\u79fb\u884c\u3057\u307e\u3059\u3002\u9000\u884c\u671f\u306f\u7d042\u301c3\u9031\u9593\u3068\u77ed\u3044\u671f\u9593\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u6bb5\u968e\u3067\u6bdb\u7403\u90e8\u304c\u7e2e\u5c0f\u3057\u3001\u6bdb\u4e73\u982d\u304b\u3089\u6bdb\u5305\u304c\u96e2\u308c\u59cb\u3081\u307e\u3059\u3002\u9aea\u306e\u6210\u9577\u306f\u4e8b\u5b9f\u4e0a\u505c\u6b62\u3057\u307e\u3059\u304c\u3001\u307e\u3060\u6bdb\u6839\u304b\u3089\u5b8c\u5168\u306b\u96e2\u8131\u3057\u3066\u306f\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-7\">\u4f11\u6b62\u671f\uff08\u30c6\u30ed\u30b2\u30f3\uff09\u3092\u7d4c\u3066\u9aea\u306f\u81ea\u7136\u306b\u629c\u3051\u843d\u3061\u308b<\/span><\/h3>\n\n\n\n<p>\u9000\u884c\u671f\u3092\u7d42\u3048\u305f\u6bdb\u5305\u306f\u3001\u7d043\u301c4\u304b\u6708\u9593\u306e\u4f11\u6b62\u671f\u306b\u5165\u308a\u307e\u3059\u3002\u4f11\u6b62\u671f\u306e\u6bdb\u5305\u306f\u6d3b\u52d5\u3092\u4f11\u3093\u3067\u3044\u308b\u72b6\u614b\u3067\u3042\u308a\u3001\u982d\u9aea\u5168\u4f53\u306e10\u301c15%\u304c\u3053\u306e\u30d5\u30a7\u30fc\u30ba\u306b\u3042\u305f\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f11\u6b62\u671f\u306e\u6700\u5f8c\u306b\u8131\u6bdb\u671f\uff08\u30a8\u30af\u30bd\u30b2\u30f3\uff09\u3092\u8fce\u3048\u3001\u53e4\u3044\u9aea\u304c\u81ea\u7136\u306b\u629c\u3051\u843d\u3061\u307e\u3059\u3002\u5065\u5eb7\u306a\u982d\u76ae\u3067\u3042\u308c\u3070\u3001\u8131\u843d\u3057\u305f\u6bdb\u5305\u304b\u3089\u518d\u3073\u65b0\u305f\u306a\u6210\u9577\u671f\u304c\u59cb\u307e\u308a\u3001\u65b0\u3057\u3044\u9aea\u304c\u751f\u3048\u3066\u304d\u307e\u3059\u30021\u65e5\u306b80\u301c100\u672c\u7a0b\u5ea6\u306e\u629c\u3051\u6bdb\u306f\u6b63\u5e38\u306a\u7bc4\u56f2\u5185\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u5404\u671f\u306e\u7279\u5fb4<\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>\u30d5\u30a7\u30fc\u30ba<\/th><th>\u671f\u9593<\/th><th>\u982d\u9aea\u306b\u5360\u3081\u308b\u5272\u5408<\/th><\/tr><\/thead><tbody><tr><td>\u6210\u9577\u671f\uff08\u30a2\u30ca\u30b2\u30f3\uff09<\/td><td>2\u301c6\u5e74<\/td><td>\u7d0485\u301c90%<\/td><\/tr><tr><td>\u9000\u884c\u671f\uff08\u30ab\u30bf\u30b2\u30f3\uff09<\/td><td>\u7d042\u301c3\u9031\u9593<\/td><td>\u7d041\u301c2%<\/td><\/tr><tr><td>\u4f11\u6b62\u671f\uff08\u30c6\u30ed\u30b2\u30f3\uff09<\/td><td>\u7d043\u301c4\u304b\u6708<\/td><td>\u7d0410\u301c15%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span id=\"DHT-2\">DHT\u304c\u6210\u9577\u671f\u3092\u77ed\u7e2e\u3055\u305b\u3066\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u304c\u4e71\u308c\u308b\u5168\u8c8c<\/span><\/h2>\n\n\n\n<p>AGA\u306e\u672c\u8cea\u306f\u3001DHT\u306e\u4f5c\u7528\u306b\u3088\u3063\u3066\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u6210\u9577\u671f\u304c\u8457\u3057\u304f\u77ed\u304f\u306a\u308b\u3053\u3068\u306b\u3042\u308a\u307e\u3059\u3002\u6210\u9577\u671f\u304c\u77ed\u7e2e\u3059\u308b\u3068\u3001\u9aea\u306f\u5341\u5206\u306b\u592a\u304f\u80b2\u3064\u524d\u306b\u9000\u884c\u671f\u3078\u79fb\u884c\u3057\u3066\u3057\u307e\u3044\u3001\u7d30\u304f\u77ed\u3044\u6bdb\u3070\u304b\u308a\u304c\u5897\u3048\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"DHTTGF\">DHT\u304c\u6bdb\u4e73\u982d\u304b\u3089TGF-\u03b2\u3092\u5206\u6ccc\u3055\u305b\u6210\u9577\u671f\u3092\u6253\u3061\u5207\u308b<\/span><\/h3>\n\n\n\n<p>DHT\u304c\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u3068\u7d50\u5408\u3057\u305f\u6bdb\u4e73\u982d\u7d30\u80de\u306f\u3001TGF-\u03b21\u3084TGF-\u03b22\u3068\u3044\u3063\u305f\u6210\u9577\u963b\u5bb3\u56e0\u5b50\u3092\u653e\u51fa\u3057\u307e\u3059\u3002TGF-\u03b2\u306f\u6bdb\u6bcd\u7d30\u80de\u306e\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff08\u8a08\u753b\u7684\u306a\u7d30\u80de\u6b7b\uff09\u3092\u8a98\u5c0e\u3057\u3001\u6210\u9577\u671f\u3092\u5f37\u5236\u7684\u306b\u7d42\u4e86\u3055\u305b\u308b\u4fe1\u53f7\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u52a0\u3048\u3066\u3001TGF-\u03b2\u306f\u6bdb\u5305\u5468\u56f2\u306e\u5fae\u5c0f\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u3082\u4f5c\u7528\u3057\u3001\u8840\u7ba1\u306e\u9000\u7e2e\u3092\u4fc3\u3057\u307e\u3059\u3002\u8840\u6d41\u304c\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3067\u6bdb\u5305\u3078\u306e\u6804\u990a\u4f9b\u7d66\u304c\u6ede\u308a\u3001\u6bdb\u5305\u306f\u3055\u3089\u306b\u5f31\u4f53\u5316\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"DKK-1Wnt\">DKK-1\u304cWnt\u30b7\u30b0\u30ca\u30eb\u3092\u906e\u65ad\u3057\u3066\u6bdb\u6bcd\u7d30\u80de\u306e\u5897\u6b96\u3092\u6b62\u3081\u308b<\/span><\/h3>\n\n\n\n<p>DHT\u306b\u3088\u3063\u3066\u6bdb\u4e73\u982d\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308bDKK-1\u306f\u3001Wnt\/\u03b2-\u30ab\u30c6\u30cb\u30f3\u7d4c\u8def\u3092\u963b\u5bb3\u3059\u308b\u7269\u8cea\u3067\u3059\u3002Wnt\u7d4c\u8def\u306f\u6bdb\u6bcd\u7d30\u80de\u306e\u5897\u6b96\u3068\u5206\u5316\u306b\u5fc5\u8981\u306a\u4fe1\u53f7\u3092\u4f1d\u3048\u308b\u305f\u3081\u3001\u3053\u306e\u7d4c\u8def\u304c\u906e\u65ad\u3055\u308c\u308b\u3068\u3001\u6bdb\u5305\u306f\u6210\u9577\u3092\u7dad\u6301\u3067\u304d\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u3067\u306f\u3001DHT\u3092\u51e6\u7406\u3057\u305f\u6bdb\u4e73\u982d\u7d30\u80de\u306eDKK-1\u767a\u73fe\u91cf\u304c\u9855\u8457\u306b\u4e0a\u6607\u3057\u3001\u6bdb\u5305\u306e\u5916\u6bdb\u6839\u9798\u7d30\u80de\u306b\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001DKK-1\u306fAGA\u306e\u9032\u884c\u306b\u304a\u3044\u3066\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">DHT\u304c\u95a2\u4e0e\u3059\u308b\u4e3b\u306a\u6210\u9577\u963b\u5bb3\u56e0\u5b50<\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>\u56e0\u5b50\u540d<\/th><th>\u4f5c\u7528<\/th><th>\u5f71\u97ff\u3092\u53d7\u3051\u308b\u7d30\u80de<\/th><\/tr><\/thead><tbody><tr><td>TGF-\u03b21<\/td><td>\u6bdb\u6bcd\u7d30\u80de\u306e\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3092\u8a98\u5c0e<\/td><td>\u6bdb\u6bcd\u7d30\u80de\u30fb\u8840\u7ba1\u5185\u76ae\u7d30\u80de<\/td><\/tr><tr><td>DKK-1<\/td><td>Wnt\/\u03b2-\u30ab\u30c6\u30cb\u30f3\u7d4c\u8def\u3092\u963b\u5bb3<\/td><td>\u5916\u6bdb\u6839\u9798\u7d30\u80de<\/td><\/tr><tr><td>IL-6<\/td><td>\u6bdb\u5e79\u306e\u4f38\u9577\u3092\u6291\u5236<\/td><td>\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u7d30\u80de<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-8\">\u6bdb\u5305\u306e\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u306f\u7e70\u308a\u8fd4\u3057\u306e\u77ed\u7e2e\u30b5\u30a4\u30af\u30eb\u3067\u9032\u884c\u3059\u308b<\/span><\/h3>\n\n\n\n<p>\u6210\u9577\u671f\u304c\u77ed\u7e2e\u3055\u308c\u305f\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u304c\u4f55\u5ea6\u3082\u7e70\u308a\u8fd4\u3055\u308c\u308b\u3046\u3061\u306b\u3001\u6bdb\u5305\u81ea\u4f53\u304c\u5f90\u3005\u306b\u5c0f\u3055\u304f\u306a\u3063\u3066\u3044\u304d\u307e\u3059\u3002\u3053\u306e\u73fe\u8c61\u3092\u300c\u6bdb\u5305\u306e\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u300d\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u592a\u3044\u7d42\u6bdb\uff08\u3057\u3063\u304b\u308a\u3057\u305f\u6bdb\u9aea\uff09\u304c\u7d30\u3044\u8edf\u6bdb\uff08\u7523\u6bdb\u306e\u3088\u3046\u306a\u6bdb\uff09\u306b\u7f6e\u304d\u63db\u308f\u308a\u3001\u5916\u898b\u4e0a\u306f\u300c\u8584\u6bdb\u300d\u3068\u3057\u3066\u8a8d\u8b58\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u6b63\u5e38\u306a\u982d\u76ae\u306e\u6210\u9577\u671f\u5bfe\u4f11\u6b62\u671f\u306e\u6bd4\u7387\u306f\u7d0412\u5bfe1\u3067\u3059\u304c\u3001AGA\u60a3\u8005\u3067\u306f5\u5bfe1\u4ee5\u4e0b\u306b\u307e\u3067\u4f4e\u4e0b\u3059\u308b\u3068\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span id=\"toc-9\">\u8584\u6bdb\u304c\u9032\u884c\u3059\u308b\u30d1\u30bf\u30fc\u30f3\u306b\u306f\u7537\u6027\u578b\u8131\u6bdb\u75c7\u306a\u3089\u3067\u306f\u306e\u7279\u5fb4\u304c\u3042\u308b<\/span><\/h2>\n\n\n\n<p>AGA\u306e\u9032\u884c\u30d1\u30bf\u30fc\u30f3\u306f\u500b\u4eba\u5dee\u304c\u3042\u308b\u3082\u306e\u306e\u3001\u591a\u304f\u306e\u5834\u5408\u306f\u751f\u3048\u969b\u306e\u5f8c\u9000\u307e\u305f\u306f\u982d\u9802\u90e8\u306e\u8584\u6bdb\u304b\u3089\u59cb\u307e\u308a\u307e\u3059\u3002\u8131\u6bdb\u304c\u8d77\u3053\u308b\u90e8\u4f4d\u3068\u8d77\u3053\u308a\u306b\u304f\u3044\u90e8\u4f4d\u304c\u660e\u78ba\u306b\u5206\u304b\u308c\u3066\u3044\u308b\u70b9\u304c\u3001AGA\u7279\u6709\u306e\u5927\u304d\u306a\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"MO\">\u751f\u3048\u969b\u3068\u3064\u3080\u3058\u304b\u3089\u5f8c\u9000\u3059\u308b\u5178\u578b\u7684\u306aM\u5b57\u30fbO\u5b57\u578b<\/span><\/h3>\n\n\n\n<p>AGA\u306e\u4ee3\u8868\u7684\u306a\u9032\u884c\u30d1\u30bf\u30fc\u30f3\u306b\u306f\u3001\u984d\u306e\u5de6\u53f3\u306e\u751f\u3048\u969b\u304c\u5f8c\u9000\u3059\u308bM\u5b57\u578b\u3068\u3001\u982d\u9802\u90e8\uff08\u3064\u3080\u3058\u5468\u8fba\uff09\u304b\u3089\u8584\u304f\u306a\u308bO\u5b57\u578b\u304c\u3042\u308a\u307e\u3059\u3002\u591a\u304f\u306e\u30b1\u30fc\u30b9\u3067\u306f\u3001\u4e21\u65b9\u304c\u540c\u6642\u306b\u9032\u884c\u3057\u3001\u3084\u304c\u3066\u524d\u982d\u90e8\u3068\u982d\u9802\u90e8\u306e\u8584\u6bdb\u304c\u5408\u6d41\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>20\u4ee3\u5f8c\u534a\u304b\u308930\u4ee3\u306b\u304b\u3051\u3066\u5909\u5316\u306b\u6c17\u3065\u304f\u65b9\u304c\u591a\u3044\u3067\u3059\u304c\u3001\u907a\u4f1d\u7684\u7d20\u56e0\u306e\u5f37\u3044\u65b9\u306f10\u4ee3\u5f8c\u534a\u304b\u3089\u5146\u5019\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u3082\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-10\">\u5074\u982d\u90e8\u3068\u5f8c\u982d\u90e8\u304c\u6b8b\u308a\u3084\u3059\u3044\u7406\u7531<\/span><\/h3>\n\n\n\n<p>AGA\u60a3\u8005\u306e\u591a\u304f\u3067\u5074\u982d\u90e8\u3068\u5f8c\u982d\u90e8\u306e\u6bdb\u9aea\u304c\u7dad\u6301\u3055\u308c\u308b\u50be\u5411\u304c\u898b\u3089\u308c\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306f\u3001\u3053\u308c\u3089\u306e\u90e8\u4f4d\u306e\u6bdb\u5305\u306b\u306fII\u578b5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u6d3b\u6027\u304c\u4f4e\u304f\u3001\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u306e\u767a\u73fe\u91cf\u3082\u5c11\u306a\u3044\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u3001DHT\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u304f\u3001\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u4e71\u308c\u304c\u751f\u3058\u306b\u304f\u3044\u306e\u3067\u3059\u3002\u690d\u6bdb\u624b\u8853\u3067\u5f8c\u982d\u90e8\u306e\u6bdb\u5305\u304c\u30c9\u30ca\u30fc\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308b\u306e\u3082\u3001\u3053\u306e\u6027\u8cea\u3092\u6d3b\u304b\u3057\u305f\u624b\u6cd5\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-11\">\u9032\u884c\u5ea6\u3092\u6e2c\u308b\u30cf\u30df\u30eb\u30c8\u30f3\u30fb\u30ce\u30fc\u30a6\u30c3\u30c9\u5206\u985e<\/span><\/h3>\n\n\n\n<p>AGA\u306e\u9032\u884c\u5ea6\u306f\u3001\u30cf\u30df\u30eb\u30c8\u30f3\u30fb\u30ce\u30fc\u30a6\u30c3\u30c9\u5206\u985e\u3068\u3044\u3046\u30b9\u30b1\u30fc\u30eb\u3092\u7528\u3044\u3066\u8a55\u4fa1\u3055\u308c\u307e\u3059\u3002I\u578b\uff08\u307b\u307c\u6b63\u5e38\uff09\u304b\u3089VII\u578b\uff08\u524d\u982d\u90e8\u3068\u982d\u9802\u90e8\u304c\u5b8c\u5168\u306b\u8131\u6bdb\u3057\u3001\u5074\u982d\u90e8\u306e\u307f\u6b8b\u5b58\uff09\u307e\u30677\u6bb5\u968e\u306b\u5206\u985e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5c02\u9580\u533b\u306e\u8a3a\u5bdf\u3067\u306f\u3053\u306e\u5206\u985e\u3092\u57fa\u6e96\u306b\u3001\u73fe\u5728\u306e\u9032\u884c\u5ea6\u3068\u4eca\u5f8c\u306e\u898b\u901a\u3057\u3092\u5224\u65ad\u3057\u307e\u3059\u3002\u65e9\u3044\u6bb5\u968e\u3067\u53d7\u8a3a\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u306e\u9078\u629e\u80a2\u304c\u5e83\u304c\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>I\u578b\u301cII\u578b\uff1a\u524d\u982d\u90e8\u306e\u751f\u3048\u969b\u304c\u308f\u305a\u304b\u306b\u5f8c\u9000\u3057\u59cb\u3081\u305f\u521d\u671f\u6bb5\u968e<\/li>\n\n\n\n<li>III\u578b\u301cIV\u578b\uff1aM\u5b57\u306e\u5f8c\u9000\u307e\u305f\u306f\u3064\u3080\u3058\u306e\u8584\u6bdb\u304c\u76ee\u7acb\u3061\u59cb\u3081\u308b\u4e2d\u671f<\/li>\n\n\n\n<li>V\u578b\u301cVII\u578b\uff1a\u524d\u982d\u90e8\u3068\u982d\u9802\u90e8\u306e\u8584\u6bdb\u304c\u5e83\u7bc4\u56f2\u306b\u53ca\u3076\u9032\u884c\u671f<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span id=\"toc-12\">\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u4e71\u3059\u751f\u6d3b\u7fd2\u6163\u306b\u5fc3\u5f53\u305f\u308a\u306f\u3042\u308a\u307e\u305b\u3093\u304b\uff1f<\/span><\/h2>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u6027\u306e\u8131\u6bdb\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3060\u3051\u3067\u6c7a\u307e\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u65e5\u3005\u306e\u751f\u6d3b\u7fd2\u6163\u304c\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001AGA\u306e\u9032\u884c\u3092\u52a0\u901f\u3055\u305b\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u898b\u76f4\u305b\u308b\u7fd2\u6163\u304b\u3089\u6539\u5584\u3092\u59cb\u3081\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-13\">\u7761\u7720\u4e0d\u8db3\u304c\u7537\u6027\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/span><\/h3>\n\n\n\n<p>\u7761\u7720\u4e2d\u306b\u306f\u6210\u9577\u30db\u30eb\u30e2\u30f3\u304c\u5206\u6ccc\u3055\u308c\u3001\u5168\u8eab\u306e\u7d44\u7e54\u4fee\u5fa9\u304c\u884c\u308f\u308c\u307e\u3059\u3002\u6162\u6027\u7684\u306a\u7761\u7720\u4e0d\u8db3\u306f\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306e\u30ea\u30ba\u30e0\u3092\u5d29\u3057\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u5206\u6ccc\u30d1\u30bf\u30fc\u30f3\u306b\u3082\u4e71\u308c\u3092\u751f\u3058\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u304c\u5897\u52a0\u3057\u3084\u3059\u304f\u306a\u308a\u3001\u9593\u63a5\u7684\u306bDHT\u306e\u751f\u6210\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-14\">\u98df\u751f\u6d3b\u306e\u504f\u308a\u304c\u982d\u76ae\u74b0\u5883\u3092\u60aa\u5316\u3055\u305b\u308b<\/span><\/h3>\n\n\n\n<p>\u8102\u8cea\u306e\u591a\u3044\u98df\u4e8b\u306b\u504f\u308b\u3068\u3001\u76ae\u8102\u5206\u6ccc\u304c\u904e\u5270\u306b\u306a\u308a\u3084\u3059\u304f\u3001\u982d\u76ae\u74b0\u5883\u304c\u60aa\u5316\u3057\u307e\u3059\u3002\u3068\u304f\u306b\u98fd\u548c\u8102\u80aa\u9178\u3084\u52d5\u7269\u6027\u8102\u80aa\u306e\u904e\u5270\u6442\u53d6\u306f\u30015\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u6d3b\u6027\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u306e\u898b\u89e3\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u4e9c\u925b\u3084\u30d3\u30bf\u30df\u30f3B\u7fa4\u3001\u9244\u5206\u306a\u3069\u306e\u6804\u990a\u7d20\u306f\u6bdb\u9aea\u306e\u6210\u9577\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u30d0\u30e9\u30f3\u30b9\u306e\u3068\u308c\u305f\u98df\u4e8b\u3092\u5fc3\u304c\u3051\u308b\u3053\u3068\u304c\u3001\u982d\u76ae\u3068\u6bdb\u5305\u306e\u5065\u5eb7\u7dad\u6301\u306b\u5bc4\u4e0e\u3059\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u9aea\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3046\u308b\u6804\u990a\u7d20\u3068\u98df\u54c1<\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>\u6804\u990a\u7d20<\/th><th>\u4e3b\u306a\u98df\u54c1\u4f8b<\/th><th>\u6bdb\u9aea\u3078\u306e\u95a2\u4e0e<\/th><\/tr><\/thead><tbody><tr><td>\u4e9c\u925b<\/td><td>\u7261\u8823\u30fb\u725b\u8d64\u8eab\u8089\u30fb\u30ca\u30c3\u30c4\u985e<\/td><td>\u6bdb\u6bcd\u7d30\u80de\u306e\u5206\u88c2\u3092\u652f\u3048\u308b<\/td><\/tr><tr><td>\u30d3\u30bf\u30df\u30f3B\u7fa4<\/td><td>\u30ec\u30d0\u30fc\u30fb\u5375\u30fb\u5927\u8c46\u88fd\u54c1<\/td><td>\u30bf\u30f3\u30d1\u30af\u8cea\u4ee3\u8b1d\u3092\u52a9\u3051\u308b<\/td><\/tr><tr><td>\u9244\u5206<\/td><td>\u307b\u3046\u308c\u3093\u8349\u30fb\u3042\u3055\u308a\u30fb\u8d64\u8eab\u9b5a<\/td><td>\u6bdb\u5305\u3078\u306e\u9178\u7d20\u904b\u642c\u306b\u95a2\u4e0e<\/td><\/tr><tr><td>\u30bf\u30f3\u30d1\u30af\u8cea<\/td><td>\u9d8f\u3080\u306d\u8089\u30fb\u9b5a\u30fb\u8c46\u8150<\/td><td>\u6bdb\u9aea\u306e\u4e3b\u6210\u5206\u30b1\u30e9\u30c1\u30f3\u306e\u539f\u6599<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-15\">\u30b9\u30c8\u30ec\u30b9\u3068\u30db\u30eb\u30e2\u30f3\u306e\u5bc6\u63a5\u306a\u95a2\u4fc2<\/span><\/h3>\n\n\n\n<p>\u7cbe\u795e\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u306f\u3001\u8996\u5e8a\u4e0b\u90e8-\u4e0b\u5782\u4f53-\u526f\u814e\u7cfb\uff08HPA\u8ef8\uff09\u3092\u901a\u3058\u3066\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5206\u6ccc\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u6162\u6027\u7684\u306a\u4e0a\u6607\u306f\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u4e71\u3059\u4e00\u56e0\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u5f37\u3044\u30b9\u30c8\u30ec\u30b9\u306f\u982d\u76ae\u306e\u8840\u7ba1\u3092\u53ce\u7e2e\u3055\u305b\u3001\u6bdb\u5305\u3078\u306e\u8840\u6d41\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u30b9\u30c8\u30ec\u30b9\u305d\u306e\u3082\u306e\u304cAGA\u306e\u76f4\u63a5\u7684\u306a\u539f\u56e0\u306b\u306a\u308b\u3068\u306f\u65ad\u8a00\u3067\u304d\u307e\u305b\u3093\u304c\u3001\u9032\u884c\u3092\u65e9\u3081\u308b\u8981\u56e0\u3068\u3057\u3066\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"DHT-3\">\u904e\u5ea6\u306a\u98f2\u9152\u30fb\u55ab\u7159\u304cDHT\u6fc3\u5ea6\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027<\/span><\/h3>\n\n\n\n<p>\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u904e\u5270\u6442\u53d6\u306f\u809d\u81d3\u3067\u306e\u30db\u30eb\u30e2\u30f3\u4ee3\u8b1d\u306b\u8ca0\u62c5\u3092\u304b\u3051\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u55ab\u7159\u306f\u982d\u76ae\u306e\u8840\u6d41\u3092\u60aa\u5316\u3055\u305b\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u5897\u5927\u3055\u305b\u3066\u6bdb\u5305\u306b\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u304b\u306d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u98f2\u9152\u3084\u55ab\u7159\u306e\u7fd2\u6163\u3092\u3059\u3050\u306b\u5b8c\u5168\u306b\u3084\u3081\u308b\u3053\u3068\u304c\u96e3\u3057\u3044\u5834\u5408\u3067\u3082\u3001\u91cf\u3092\u6e1b\u3089\u3059\u52aa\u529b\u306f\u982d\u76ae\u74b0\u5883\u306e\u6539\u5584\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u5c0f\u3055\u306a\u7a4d\u307f\u91cd\u306d\u304c\u3001\u30db\u30eb\u30e2\u30f3\u6027\u8131\u6bdb\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u52a9\u3051\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span id=\"toc-16\">\u533b\u7642\u6a5f\u95a2\u3067\u53d7\u3051\u3089\u308c\u308b\u30db\u30eb\u30e2\u30f3\u6027\u8131\u6bdb\u3078\u306e\u5bfe\u51e6\u6cd5<\/span><\/h2>\n\n\n\n<p>AGA\u306f\u9032\u884c\u6027\u306e\u8131\u6bdb\u75c7\u3067\u3042\u308b\u305f\u3081\u3001\u65e9\u671f\u306b\u9069\u5207\u306a\u5bfe\u51e6\u3092\u884c\u3046\u3053\u3068\u3067\u9032\u884c\u3092\u9045\u3089\u305b\u305f\u308a\u3001\u6bdb\u9aea\u306e\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u305f\u308a\u3057\u307e\u3059\u3002\u73fe\u5728\u3001\u533b\u7642\u6a5f\u95a2\u3067\u51e6\u65b9\u3055\u308c\u308b\u4ee3\u8868\u7684\u306a\u6cbb\u7642\u85ac\u306f\u30015\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\u3068\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306e2\u7a2e\u985e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"5\">5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\uff08\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u30fb\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\uff09<\/span><\/h3>\n\n\n\n<p>\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306fII\u578b5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u3092\u9078\u629e\u7684\u306b\u963b\u5bb3\u3059\u308b\u7d4c\u53e3\u85ac\u3067\u3001DHT\u751f\u6210\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u6bdb\u5305\u306e\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u306e\u9032\u884c\u3092\u9632\u304e\u307e\u3059\u3002\u56fd\u5185\u5916\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u3001\u982d\u9802\u90e8\u306e\u6bdb\u9aea\u6570\u306e\u5897\u52a0\u3084\u9032\u884c\u306e\u6291\u5236\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306fI\u578b\u3068II\u578b\u306e\u4e21\u65b9\u3092\u963b\u5bb3\u3059\u308b\u305f\u3081\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3088\u308a\u3082\u5e83\u7bc4\u306aDHT\u6291\u5236\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u3082\u533b\u5e2b\u3068\u5341\u5206\u306b\u76f8\u8ac7\u3057\u305f\u3046\u3048\u3067\u4f7f\u7528\u3059\u308b\u3079\u304d\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-17\">\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306e\u8840\u884c\u4fc3\u9032\u4f5c\u7528\u3067\u6bdb\u5305\u3092\u6d3b\u6027\u5316\u3055\u305b\u308b<\/span><\/h3>\n\n\n\n<p>\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306f\u5916\u7528\u85ac\u3068\u3057\u3066\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u982d\u76ae\u306e\u8840\u7ba1\u62e1\u5f35\u4f5c\u7528\u3092\u901a\u3058\u3066\u6bdb\u5305\u3078\u306e\u8840\u6d41\u3092\u5897\u3084\u3057\u3001\u6bdb\u6bcd\u7d30\u80de\u306e\u6d3b\u52d5\u3092\u4fc3\u3059\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u3082\u3068\u3082\u3068\u306f\u9ad8\u8840\u5727\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u304c\u3001\u526f\u4f5c\u7528\u3068\u3057\u3066\u767a\u6bdb\u304c\u8a8d\u3081\u3089\u308c\u305f\u3053\u3068\u304b\u3089\u8131\u6bdb\u6cbb\u7642\u306b\u8ee2\u7528\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306fDHT\u306e\u751f\u6210\u3092\u76f4\u63a5\u963b\u5bb3\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u305f\u3081\u30015\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\u3068\u306e\u4f75\u7528\u304c\u52b9\u679c\u7684\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5857\u5e03\u5f8c\u306e\u304b\u3086\u307f\u3084\u982d\u76ae\u306e\u4e7e\u71e5\u304c\u51fa\u308b\u5834\u5408\u306f\u3001\u4f7f\u7528\u65b9\u6cd5\u306b\u3064\u3044\u3066\u533b\u5e2b\u306b\u78ba\u8a8d\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-18\">\u81ea\u5206\u306b\u5408\u3063\u305f\u80b2\u6bdb\u5264\u9078\u3073\u3067\u62bc\u3055\u3048\u3066\u304a\u304d\u305f\u3044\u6210\u5206<\/span><\/h3>\n\n\n\n<p>\u533b\u7642\u6a5f\u95a2\u3067\u306e\u51e6\u65b9\u85ac\u4ee5\u5916\u306b\u3082\u3001\u5e02\u8ca9\u306e\u80b2\u6bdb\u5264\u306b\u306f\u3055\u307e\u3056\u307e\u306a\u6709\u52b9\u6210\u5206\u304c\u914d\u5408\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6210\u5206\u8868\u793a\u3092\u78ba\u8a8d\u3057\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306e\u3042\u308b\u6210\u5206\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u5224\u65ad\u57fa\u6e96\u306b\u3059\u308b\u3053\u3068\u304c\u8ce2\u660e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u80b2\u6bdb\u5264\u306f\u5373\u52b9\u6027\u3092\u6c42\u3081\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u7d99\u7d9a\u7684\u306b\u4f7f\u3046\u3053\u3068\u3067\u982d\u76ae\u74b0\u5883\u3092\u6574\u3048\u3001\u6bdb\u5305\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u76ee\u7684\u3067\u6d3b\u7528\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u6c17\u306b\u306a\u308b\u88fd\u54c1\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u533b\u5e2b\u3084\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3057\u3066\u304b\u3089\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u6210\u5206\u3092\u542b\u3080\u5916\u7528\u88fd\u5264<\/li>\n\n\n\n<li>\u8840\u884c\u4fc3\u9032\u3092\u76ee\u7684\u3068\u3057\u305f\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u914d\u5408\u88fd\u54c1<\/li>\n\n\n\n<li>\u6297\u708e\u75c7\u30fb\u6297\u9178\u5316\u4f5c\u7528\u306e\u3042\u308b\u690d\u7269\u7531\u6765\u30a8\u30ad\u30b9\u914d\u5408\u54c1<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span id=\"toc-19\">\u65e9\u3081\u306e\u5bfe\u7b56\u304c\u30ab\u30ae\uff5c\u30db\u30eb\u30e2\u30f3\u6027\u8131\u6bdb\u3068\u4e0a\u624b\u306b\u5411\u304d\u5408\u3046\u305f\u3081\u306e\u5fc3\u69cb\u3048<\/span><\/h2>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u8131\u6bdb\u306f\u653e\u7f6e\u3059\u308c\u3070\u78ba\u5b9f\u306b\u9032\u884c\u3057\u307e\u3059\u304c\u3001\u65e9\u3044\u6bb5\u968e\u3067\u5bfe\u51e6\u3059\u308c\u3070\u6539\u5584\u306e\u53ef\u80fd\u6027\u306f\u5341\u5206\u306b\u3042\u308a\u307e\u3059\u3002\u7126\u308a\u3059\u304e\u305a\u3001\u6b63\u3057\u3044\u77e5\u8b58\u306b\u57fa\u3065\u3044\u3066\u7740\u5b9f\u306b\u884c\u52d5\u3059\u308b\u3053\u3068\u304c\u3001\u7d50\u679c\u3078\u306e\u8fd1\u9053\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-20\">\u8131\u6bdb\u306b\u6c17\u3065\u3044\u305f\u3089\u307e\u305a\u306f\u5c02\u9580\u533b\u306b\u76f8\u8ac7\u3059\u308b\u3079\u304d<\/span><\/h3>\n\n\n\n<p>\u629c\u3051\u6bdb\u306e\u5897\u52a0\u3084\u9aea\u306e\u30dc\u30ea\u30e5\u30fc\u30e0\u4f4e\u4e0b\u3092\u611f\u3058\u305f\u6642\u70b9\u3067\u3001\u76ae\u819a\u79d1\u3084AGA\u5c02\u9580\u30af\u30ea\u30cb\u30c3\u30af\u3092\u53d7\u8a3a\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002\u81ea\u5df1\u5224\u65ad\u3067\u5e02\u8ca9\u54c1\u306e\u307f\u306b\u983c\u308b\u3068\u3001\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u3044\u307e\u307e\u8cb4\u91cd\u306a\u6642\u9593\u3092\u5931\u3063\u3066\u3057\u307e\u3046\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u5c02\u9580\u533b\u306f\u30de\u30a4\u30af\u30ed\u30b9\u30b3\u30fc\u30d7\u3067\u306e\u982d\u76ae\u8a3a\u65ad\u3084\u30cf\u30df\u30eb\u30c8\u30f3\u30fb\u30ce\u30fc\u30a6\u30c3\u30c9\u5206\u985e\u306b\u3088\u308b\u9032\u884c\u5ea6\u8a55\u4fa1\u3092\u884c\u3044\u3001\u500b\u3005\u306e\u72b6\u614b\u306b\u5fdc\u3058\u305f\u6cbb\u7642\u65b9\u91dd\u3092\u63d0\u6848\u3057\u3066\u304f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u53d7\u8a3a\u524d\u306b\u78ba\u8a8d\u3057\u3066\u304a\u304f\u3068\u5f79\u7acb\u3064\u60c5\u5831<\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>\u78ba\u8a8d\u9805\u76ee<\/th><th>\u5177\u4f53\u7684\u306a\u5185\u5bb9<\/th><\/tr><\/thead><tbody><tr><td>\u5bb6\u65cf\u6b74<\/td><td>\u7236\u65b9\u30fb\u6bcd\u65b9\u306b\u8584\u6bdb\u306e\u65b9\u304c\u3044\u308b\u304b<\/td><\/tr><tr><td>\u8131\u6bdb\u306b\u6c17\u3065\u3044\u305f\u6642\u671f<\/td><td>\u3044\u3064\u9803\u304b\u3089\u629c\u3051\u6bdb\u304c\u5897\u3048\u305f\u304b<\/td><\/tr><tr><td>\u73fe\u5728\u306e\u670d\u85ac\u72b6\u6cc1<\/td><td>\u5e38\u7528\u85ac\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u7a2e\u985e<\/td><\/tr><tr><td>\u751f\u6d3b\u7fd2\u6163<\/td><td>\u7761\u7720\u6642\u9593\u30fb\u98df\u4e8b\u30fb\u55ab\u7159\u30fb\u98f2\u9152\u306e\u983b\u5ea6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"toc-21\">\u7d99\u7d9a\u3057\u305f\u6cbb\u7642\u3068\u30bb\u30eb\u30d5\u30b1\u30a2\u306e\u4e21\u7acb\u304c\u6210\u679c\u306b\u3064\u306a\u304c\u308b<\/span><\/h3>\n\n\n\n<p>AGA\u6cbb\u7642\u306f\u300c\u7d9a\u3051\u308b\u3053\u3068\u300d\u304c\u4f55\u3088\u308a\u3082\u5927\u5207\u3067\u3059\u3002\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3084\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306f\u3001\u670d\u7528\u30fb\u5857\u5e03\u3092\u4e2d\u6b62\u3059\u308b\u3068\u518d\u3073\u8131\u6bdb\u304c\u9032\u884c\u3059\u308b\u30b1\u30fc\u30b9\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6cbb\u7642\u85ac\u3060\u3051\u306b\u983c\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u30d0\u30e9\u30f3\u30b9\u306e\u826f\u3044\u98df\u4e8b\u3001\u5341\u5206\u306a\u7761\u7720\u3001\u9069\u5ea6\u306a\u904b\u52d5\u306a\u3069\u306e\u30bb\u30eb\u30d5\u30b1\u30a2\u3092\u4e26\u884c\u3057\u3066\u884c\u3046\u3053\u3068\u3067\u3001\u3088\u308a\u826f\u3044\u7d50\u679c\u3092\u5f97\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span id=\"1\">\u7126\u308a\u306f\u7981\u7269\u3001\u534a\u5e74\u304b\u30891\u5e74\u306e\u30b9\u30d1\u30f3\u3067\u7d4c\u904e\u3092\u898b\u5b88\u308b<\/span><\/h3>\n\n\n\n<p>AGA\u6cbb\u7642\u306e\u52b9\u679c\u304c\u76ee\u306b\u898b\u3048\u3066\u304f\u308b\u307e\u3067\u306b\u306f\u3001\u4e00\u822c\u7684\u306b3\u301c6\u304b\u6708\u4ee5\u4e0a\u306e\u6642\u9593\u304c\u304b\u304b\u308a\u307e\u3059\u3002\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u5468\u671f\u3092\u8003\u3048\u308b\u3068\u3001\u6cbb\u7642\u958b\u59cb\u304b\u3089\u534a\u5e74\u301c1\u5e74\u7a0b\u5ea6\u3092\u304b\u3051\u3066\u52b9\u679c\u3092\u5224\u5b9a\u3059\u308b\u306e\u304c\u59a5\u5f53\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u300c\u306a\u304b\u306a\u304b\u5909\u5316\u304c\u306a\u3044\u300d\u3068\u611f\u3058\u3066\u9014\u4e2d\u3067\u6cbb\u7642\u3092\u3084\u3081\u3066\u3057\u307e\u3046\u65b9\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u3057\u305f\u6bdb\u5305\u304c\u518d\u3073\u592a\u3044\u6bdb\u3092\u751f\u3084\u3059\u306b\u306f\u6642\u9593\u3092\u8981\u3057\u307e\u3059\u3002\u5b9a\u671f\u7684\u306b\u533b\u5e2b\u306e\u8a3a\u5bdf\u3092\u53d7\u3051\u3001\u7d4c\u904e\u3092\u78ba\u8a8d\u3057\u306a\u304c\u3089\u6839\u6c17\u3088\u304f\u7d9a\u3051\u308b\u3053\u3068\u304c\u3001\u6539\u5584\u3078\u306e\u78ba\u304b\u306a\u9053\u7b4b\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"qa-heading\"><span id=\"toc-22\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/span><\/h2>\n\n\n\n<div class=\"wp-block-hannya-blocks-qas\" itemscope itemtype=\"https:\/\/schema.org\/FAQPage\">\n<div class=\"wp-block-hannya-blocks-qa hannya-block-qa\" itemscope itemprop=\"mainEntity\" itemtype=\"https:\/\/schema.org\/Question\"><div class=\"question q_block q_red\" style=\"display:flex\"><div class=\"q_mark\">Q<\/div><div class=\"q_content\" itemprop=\"name\"><div>\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u8131\u6bdb\u306f\u3069\u306e\u5e74\u9f62\u304b\u3089\u59cb\u307e\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u304b\uff1f<\/div><\/div><\/div><div class=\"a_block_wrapper\"><div class=\"a_block a_blue\" style=\"display:flex\" itemscope itemprop=\"acceptedAnswer\" itemtype=\"https:\/\/schema.org\/Answer\"><div class=\"a_mark\" style=\"border-color:\">A<\/div><div class=\"a_content\" itemprop=\"text\"><div class=\"a_title\">\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u8131\u6bdb\uff08AGA\uff09\u306f\u3001\u601d\u6625\u671f\u4ee5\u964d\u3067\u3042\u308c\u3070\u3069\u306e\u5e74\u9f62\u304b\u3089\u3067\u3082\u59cb\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u822c\u7684\u306b\u306f20\u4ee3\u5f8c\u534a\u304b\u308930\u4ee3\u306b\u304b\u3051\u3066\u5909\u5316\u306b\u6c17\u3065\u304f\u65b9\u304c\u591a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u305f\u3060\u3057\u3001\u907a\u4f1d\u7684\u7d20\u56e0\u304c\u5f37\u3044\u5834\u5408\u306b\u306f10\u4ee3\u5f8c\u534a\u304b\u3089\u524d\u982d\u90e8\u306e\u751f\u3048\u969b\u306b\u5909\u5316\u304c\u73fe\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u300c\u307e\u3060\u82e5\u3044\u304b\u3089\u5927\u4e08\u592b\u300d\u3068\u601d\u308f\u305a\u3001\u629c\u3051\u6bdb\u304c\u5897\u3048\u305f\u3068\u611f\u3058\u305f\u3089\u65e9\u3081\u306b\u5c02\u9580\u533b\u3078\u76f8\u8ac7\u3059\u308b\u3053\u3068\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/div><div class=\"a_text_off\"><\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hannya-blocks-qa hannya-block-qa\" itemscope itemprop=\"mainEntity\" itemtype=\"https:\/\/schema.org\/Question\"><div class=\"question q_block q_red\" style=\"display:flex\"><div class=\"q_mark\">Q<\/div><div class=\"q_content\" itemprop=\"name\"><div>DHT\u3092\u6e1b\u3089\u305b\u3070\u30db\u30eb\u30e2\u30f3\u6027\u306e\u8131\u6bdb\u306f\u5b8c\u5168\u306b\u6b62\u3081\u3089\u308c\u307e\u3059\u304b\uff1f<\/div><\/div><\/div><div class=\"a_block_wrapper\"><div class=\"a_block a_blue\" style=\"display:flex\" itemscope itemprop=\"acceptedAnswer\" itemtype=\"https:\/\/schema.org\/Answer\"><div class=\"a_mark\" style=\"border-color:\">A<\/div><div class=\"a_content\" itemprop=\"text\"><div class=\"a_title\">DHT\u306e\u751f\u6210\u3092\u6291\u3048\u308b\u3053\u3068\u3067AGA\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u305f\u308a\u3001\u6bdb\u9aea\u306e\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u305f\u308a\u3057\u307e\u3059\u304c\u3001\u5b8c\u5168\u306b\u8131\u6bdb\u3092\u6b62\u3081\u3089\u308c\u308b\u304b\u3069\u3046\u304b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3084\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306fDHT\u751f\u6210\u3092\u52b9\u679c\u7684\u306b\u6291\u5236\u3057\u307e\u3059\u304c\u3001\u3059\u3067\u306b\u9ad8\u5ea6\u306b\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u3057\u305f\u6bdb\u5305\u3092\u5143\u901a\u308a\u306b\u56de\u5fa9\u3055\u305b\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<br>\u305d\u306e\u305f\u3081\u3001\u6bdb\u5305\u306e\u840e\u7e2e\u304c\u9032\u3080\u524d\u306e\u3067\u304d\u308b\u3060\u3051\u65e9\u3044\u6bb5\u968e\u3067\u6cbb\u7642\u3092\u958b\u59cb\u3059\u308b\u3053\u3068\u304c\u3001\u826f\u3044\u7d50\u679c\u306b\u3064\u306a\u304c\u308a\u3084\u3059\u3044\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/div><div class=\"a_text_off\"><\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hannya-blocks-qa hannya-block-qa\" itemscope itemprop=\"mainEntity\" itemtype=\"https:\/\/schema.org\/Question\"><div class=\"question q_block q_red\" style=\"display:flex\"><div class=\"q_mark\">Q<\/div><div class=\"q_content\" itemprop=\"name\"><div>\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u4e71\u308c\u306f\u81ea\u5206\u3067\u78ba\u8a8d\u3067\u304d\u307e\u3059\u304b\uff1f<\/div><\/div><\/div><div class=\"a_block_wrapper\"><div class=\"a_block a_blue\" style=\"display:flex\" itemscope itemprop=\"acceptedAnswer\" itemtype=\"https:\/\/schema.org\/Answer\"><div class=\"a_mark\" style=\"border-color:\">A<\/div><div class=\"a_content\" itemprop=\"text\"><div class=\"a_title\">\u3054\u81ea\u8eab\u3067\u30d8\u30a2\u30b5\u30a4\u30af\u30eb\u306e\u4e71\u308c\u3092\u6b63\u78ba\u306b\u5224\u5b9a\u3059\u308b\u306e\u306f\u56f0\u96e3\u3067\u3059\u304c\u3001\u3044\u304f\u3064\u304b\u306e\u30b5\u30a4\u30f3\u306b\u6ce8\u76ee\u3059\u308b\u3053\u3068\u3067\u7570\u5909\u306b\u6c17\u3065\u304f\u3053\u3068\u306f\u53ef\u80fd\u3067\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u629c\u3051\u6bdb\u306e\u672c\u6570\u304c1\u65e5150\u672c\u3092\u8d85\u3048\u308b\u72b6\u614b\u304c\u7d9a\u3044\u305f\u308a\u3001\u629c\u3051\u305f\u6bdb\u306e\u6839\u5143\u304c\u7d30\u304f\u77ed\u304b\u3063\u305f\u308a\u3059\u308b\u5834\u5408\u306f\u3001\u6210\u9577\u671f\u306e\u77ed\u7e2e\u304c\u7591\u308f\u308c\u307e\u3059\u3002<br>\u3088\u308a\u6b63\u78ba\u306a\u5224\u65ad\u3092\u5f97\u308b\u306b\u306f\u3001\u76ae\u819a\u79d1\u3084AGA\u5c02\u9580\u30af\u30ea\u30cb\u30c3\u30af\u3067\u30de\u30a4\u30af\u30ed\u30b9\u30b3\u30fc\u30d7\u3092\u7528\u3044\u305f\u982d\u76ae\u691c\u67fb\u3092\u53d7\u3051\u308b\u3053\u3068\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002\u6bdb\u9aea\u306e\u592a\u3055\u3084\u6210\u9577\u671f\u6bdb\u3068\u4f11\u6b62\u671f\u6bdb\u306e\u6bd4\u7387\u3092\u5ba2\u89b3\u7684\u306b\u628a\u63e1\u3067\u304d\u307e\u3059\u3002<\/div><div class=\"a_text_off\"><\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hannya-blocks-qa hannya-block-qa\" itemscope itemprop=\"mainEntity\" itemtype=\"https:\/\/schema.org\/Question\"><div class=\"question q_block q_red\" style=\"display:flex\"><div class=\"q_mark\">Q<\/div><div class=\"q_content\" itemprop=\"name\"><div>\u7537\u6027\u578b\u8131\u6bdb\u75c7\u3068\u52a0\u9f62\u306b\u3088\u308b\u8584\u6bdb\u306e\u9055\u3044\u306f\u4f55\u3067\u3059\u304b\uff1f<\/div><\/div><\/div><div class=\"a_block_wrapper\"><div class=\"a_block a_blue\" style=\"display:flex\" itemscope itemprop=\"acceptedAnswer\" itemtype=\"https:\/\/schema.org\/Answer\"><div class=\"a_mark\" style=\"border-color:\">A<\/div><div class=\"a_content\" itemprop=\"text\"><div class=\"a_title\">\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u306fDHT\u306e\u4f5c\u7528\u306b\u3088\u3063\u3066\u7279\u5b9a\u306e\u30d1\u30bf\u30fc\u30f3\uff08\u524d\u982d\u90e8\u3084\u982d\u9802\u90e8\uff09\u3067\u6bdb\u5305\u304c\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u3059\u308b\u75be\u60a3\u3067\u3059\u3002\u4e00\u65b9\u3001\u52a0\u9f62\u306b\u3088\u308b\u8584\u6bdb\u306f\u982d\u76ae\u5168\u4f53\u3067\u6bdb\u5305\u306e\u6a5f\u80fd\u304c\u5f90\u3005\u306b\u4f4e\u4e0b\u3059\u308b\u81ea\u7136\u306a\u8001\u5316\u73fe\u8c61\u3067\u3042\u308a\u3001\u7279\u5b9a\u306e\u90e8\u4f4d\u306b\u96c6\u4e2d\u3057\u306b\u304f\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<br>AGA\u306f20\u4ee3\u304b\u3089\u59cb\u307e\u308b\u3053\u3068\u3082\u3042\u308b\u306e\u306b\u5bfe\u3057\u3001\u52a0\u9f62\u6027\u306e\u8584\u6bdb\u306f50\u4ee3\u4ee5\u964d\u306b\u76ee\u7acb\u3061\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u9032\u884c\u30d1\u30bf\u30fc\u30f3\u3084\u767a\u75c7\u5e74\u9f62\u306e\u9055\u3044\u304b\u3089\u3001\u5c02\u9580\u533b\u306f\u4e21\u8005\u3092\u533a\u5225\u3057\u3066\u8a3a\u65ad\u3057\u307e\u3059\u3002<\/div><div class=\"a_text_off\"><\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hannya-blocks-qa hannya-block-qa\" itemscope itemprop=\"mainEntity\" itemtype=\"https:\/\/schema.org\/Question\"><div class=\"question q_block q_red\" style=\"display:flex\"><div class=\"q_mark\">Q<\/div><div class=\"q_content\" itemprop=\"name\"><div>\u80b2\u6bdb\u5264\u3060\u3051\u3067\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u8131\u6bdb\u306f\u6539\u5584\u3067\u304d\u307e\u3059\u304b\uff1f<\/div><\/div><\/div><div class=\"a_block_wrapper\"><div class=\"a_block a_blue\" style=\"display:flex\" itemscope itemprop=\"acceptedAnswer\" itemtype=\"https:\/\/schema.org\/Answer\"><div class=\"a_mark\" style=\"border-color:\">A<\/div><div class=\"a_content\" itemprop=\"text\"><div class=\"a_title\">\u5e02\u8ca9\u306e\u80b2\u6bdb\u5264\u306f\u982d\u76ae\u74b0\u5883\u3092\u6574\u3048\u305f\u308a\u8840\u884c\u3092\u4fc3\u9032\u3057\u305f\u308a\u3059\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u304c\u3001DHT\u751f\u6210\u3092\u76f4\u63a5\u7684\u306b\u6291\u5236\u3059\u308b\u529b\u306f\u9650\u5b9a\u7684\u3067\u3059\u3002\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u8131\u6bdb\u306e\u6839\u672c\u7684\u306a\u539f\u56e0\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u306b\u306f\u3001\u533b\u5e2b\u306e\u51e6\u65b9\u306b\u3088\u308b5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\u306e\u4f75\u7528\u304c\u52b9\u679c\u7684\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u80b2\u6bdb\u5264\u306f\u3042\u304f\u307e\u3067\u88dc\u52a9\u7684\u306a\u4f4d\u7f6e\u3065\u3051\u3068\u3057\u3066\u6d3b\u7528\u3057\u3001\u6cbb\u7642\u306e\u4e3b\u8ef8\u306f\u5c02\u9580\u533b\u306e\u6307\u5c0e\u306e\u3082\u3068\u3067\u6c7a\u3081\u308b\u3053\u3068\u304c\u671b\u307e\u3057\u3044\u3067\u3057\u3087\u3046\u3002\u80b2\u6bdb\u5264\u3068\u6cbb\u7642\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u76f8\u4e57\u7684\u306a\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/div><div class=\"a_text_off\"><\/div><\/div><\/div><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-hannya-blocks-accordion  hbb_accordion js-accordion\"><div class=\"hbb_accordion-title js-accordion_title mark_plus mark_right\" style=\"border-width:0px;border-radius:5px\">Reference<\/div><div class=\"hbb_accordion-content js-accordion_content hbb_accordion-list ind_mt\">\n<p>Fu, D., Huang, J., Li, K., Chen, Y., He, Y., Sun, Y., Guo, Y., Du, L., Qu, Q., Miao, Y., &amp; Hu, Z. (2021). Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia. Biomedicine &amp; Pharmacotherapy, 137, 111247. https:\/\/doi.org\/10.1016\/j.biopha.2021.111247<\/p>\n\n\n\n<p>Tr\u00fceb, R. M. (2002). Molecular mechanisms of androgenetic alopecia. Experimental Gerontology, 37(8\u20139), 981\u2013990. https:\/\/doi.org\/10.1016\/s0531-5565(02)00093-1<\/p>\n\n\n\n<p>Kaufman, K. D. (2002). Androgens and alopecia. Molecular and Cellular Endocrinology, 198(1\u20132), 89\u201395. https:\/\/doi.org\/10.1016\/s0303-7207(02)00372-6<\/p>\n\n\n\n<p>Inui, S., &amp; Itami, S. (2011). Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla. Journal of Dermatological Science, 61(1), 1\u20136. https:\/\/doi.org\/10.1016\/j.jdermsci.2010.10.015<\/p>\n\n\n\n<p>Inui, S., &amp; Itami, S. (2013). Androgen actions on the human hair follicle: Perspectives. Experimental Dermatology, 22(3), 168\u2013171. https:\/\/doi.org\/10.1111\/exd.12024<\/p>\n\n\n\n<p>Hibberts, N. A., Howell, A. E., &amp; Randall, V. A. (1998). Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp. Journal of Endocrinology, 156(1), 59\u201365. https:\/\/doi.org\/10.1677\/joe.0.1560059<\/p>\n\n\n\n<p>Randall, V. A. (2008). Androgens and hair growth. Dermatologic Therapy, 21(5), 314\u2013328. https:\/\/doi.org\/10.1111\/j.1529-8019.2008.00214.x<\/p>\n\n\n\n<p>Kwack, M. H., Sung, Y. K., Chung, E. J., Im, S. U., Ahn, J. S., Kim, M. K., &amp; Kim, J. C. (2008). Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes. Journal of Investigative Dermatology, 128(2), 262\u2013269. https:\/\/doi.org\/10.1038\/sj.jid.5700999<\/p>\n\n\n\n<p>Chen, X., Liu, B., Li, Y., Han, L., Tang, X., Deng, W., Lai, W., &amp; Wan, M. (2020). Dihydrotestosterone regulates hair growth through the Wnt\/\u03b2-catenin pathway in C57BL\/6 mice and in vitro organ culture. Frontiers in Pharmacology, 10, 1528. https:\/\/doi.org\/10.3389\/fphar.2019.01528<\/p>\n\n\n\n<p>Randall, V. A. (2007). Hormonal regulation of hair follicles exhibits a biological paradox. 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